MOTS-c is a mitochondria-derived peptide studied in human research for its role in cellular energy regulation and metabolic health. Clinical studies have explored its potential to support mitochondrial function, enhance glucose metabolism, and influence muscle energy utilization under controlled conditions. Research has also investigated MOTS-c’s effects on insulin sensitivity, metabolic signaling pathways, and age-related cellular function. Human studies suggest it may play a role in maintaining energy balance and overall metabolic resilience. Across published research, MOTS-c has proven valuable as a tool for studying mitochondrial biology, metabolism, and cellular health. Research Use Only. Not for Human or Veterinarian Use.