Melanotan II is a synthetic peptide studied in human research for its effects on melanocortin receptor pathways. Clinical studies have explored its potential to influence pigmentation, including the stimulation of melanin production in the skin. Research has also investigated its role in supporting sexual function and appetite regulation through melanocortin signaling. Human trials have demonstrated that Melanotan II can affect energy balance, pigmentation responses, and hormonal pathways under controlled conditions. Across published studies, Melanotan II has served as a valuable tool for understanding melanocortin receptor activity and related physiological processes. Research Use Only. Not For Human or Veterinary Use.